Compass Pathways’ COM360 program has reached Phase 3 endpoints. In clinical terms, this is a data milestone. In cultural terms, it is a bell tolling across the mental health landscape.

How to prepare with Beyond Consulting

If you’ve ever laid in that liminal space between sleep and wakefulness, where images are vivid, emotions intense, and time elusive, you’ve brushed the very terrain explored by a new scientific proposal that’s been rippling through psychedelic theory: the oneirogen hypothesis.

Psychedelics may serve as a potential treatment for addiction, offering a novel approach that targets the emotional, psychological, and neurochemical roots of substance use disorders. Substances like psilocybin and LSD, for example, are believed to disrupt habitual thought patterns and promote introspection, facilitating emotional healing. While ibogaine, the psychoactive alkaloid derived from the iboga plant, can also foster deep insight, it is also believed to help with addiction by modulating the brain’s dopaminergic and opioid systems, reducing withdrawal symptoms and cravings.

Psychedelic-assisted therapies for women’s health offer a different lens. One that recognizes women’s health transitions as whole-system events, involving brain chemistry, nervous system regulation, emotional processing, and identity reorganization all at once.

How to Work With GALILEA®

Jan 3

Written By Stephanie Karzon

A Practical Guide for Clinics, Practices, and Providers

GALILEA® works with providers, clinics, and psychedelic therapy centers as a strategic and clinical partner. Our offerings are designed to meet you where you are—whether you’re seeking expert perspective, refining an existing practice, or building something entirely new.

All engagements are provider-to-provider and consultant-to-practice, and each tier includes access to our broader multidisciplinary expert team as needed. This allows us to match the right expertise to your specific clinical or operational questions.

GALILEA® is a multidisciplinary program teaching cycle-aware care as both a clinical and relational practice.

GALILEA® brings together psychedelic-informed practice, women-centered precision medicine, operational excellence, and data you can trust into a cohesive program that clinics, therapeutic centers, and practitioners can adopt and evolve within their own ecosystems.

There's a peculiar moment happening in wellness right now. On one hand, we have NASA-grade biofeedback devices and FDA-approved digital therapeutics. On the other, we have people lying on vibrating beds claiming to access "non-ordinary states of consciousness." And, both might be onto something.

Neuroplasticity, psychedelics, and buzz.
The pons, a region involved in movement and implicated in consciousness.
Source: https://www.gregadunn.com/self-reflected/self-reflected-gallery/

When Psychedelics Meet an Injured Spinal Cord – What Really Happens?

Peripherally Dominant Serotonin-Like Syndrome in Persons With SCI Using Serotonergic Psychedelics

In people with spinal cord injury (SCI), something different can happen when taking serotonergic psychedelics like psilocybin or LSD: an intense peripheral reaction in the body that can look a lot like a mild or localized form of serotonin syndrome.

Psilocybin—the psychedelic compound found in certain mushrooms—has long been studied for its impact on mood, consciousness, and mental health. But could it also affect the body in ways we hadn’t considered? A new study, published in npj Aging (July 2025) by Kosuke Kato and colleagues, offers the first experimental evidence that psilocybin and its active metabolite, psilocin, may also have anti-aging effects at both the cellular and organismal level.

Across time and culture, music has served as a sacred technology for transformation. From the rhythmic drumming of the Celts, Inca, Zhou, and Māori to the harmonic chants of Tibetan monks, ancient peoples used sound to connect with the divine, each other, and the rhythms of the earth. These ceremonial traditions weren’t just spiritual—they were communal, grounding, and transcendent. Today’s ceremonial music may sound different, but it echoes the same timeless intent: to guide the human spirit through moments of awakening, healing, and connection.

Mushrooms have enchanted humans for thousands of years—hailed as sacred, medicinal, and even immortal. From ancient Egyptian pharaohs calling them “plants of immortality” to their revered role in traditional Chinese medicine and Indigenous ceremonies, fungi have always held a mysterious kind of magic. Today, functional mushrooms are making a fierce comeback, not just in soups and supplements, but in science-backed wellness routines. Packed with powerful compounds like beta-glucans and antioxidants, they’re being studied—and celebrated—for boosting immunity, brain power, and vitality.

Mental Health Crises in The ER and A New Opportunity for Ketamine

How Psychedelics and Your Gut Microbiome Might Work Together for Mental Health

A Summary of: "Seeking the Psilocybiome: Psychedelics Meet the Microbiota-Gut-Brain Axis" by Kelly et al.

Growth Isn’t Always Pretty

The Messy Necessary Truth About Psychedelic Healing

If you’re seeking a perfectly smooth, euphoric, Instagram-worthy path to mental well-being through psychedelics, I hate to break it to you, but you might be better off with a scented candle and a meditation app.

GLP-1s for Fat Loss: But What About Our Muscle

while these medications can help shed pounds, an important question remains: are we prioritizing our muscle mass as much as fat loss? Beneath the excitement lies a hidden concern about America’s “muscle deficit” —not just as a gym problem, but a nationwide shortfall in strength, resilience, and metabolic health. If fat is the villain, muscles are the unsung heroes of longevity—and preserving them is far more crucial than many realize.

2024 in review